Achivements

 Scientific Publications     

1.Vadgama VK, Patel YA, Patel TK, Tripathi CB. Pharmacodynamic interaction between pantoprazole and vecuronium at neuromuscular junction. Auton Autacoid Pharmacol. 2011 Jan;31(1-2):31-5.

2 Sanmukhani J, Anovadiya A, Tripathi CB. Evaluation of antidepressant like activity of curcumin and its combination with fluoxetine and imipramine: an acute and chronic study. Acta Poloniae Pharmaceutica  Drug Research.5; 2011.

3. Patel YA, Vadgama VK, Baxi SN, Tripathi CB. Evolution of Hypolipidemic Activity of Leaf Juice of Catharanthus roseus (Linn.) G. Donn. In Guinea Pigs. Acta Poloniae Pharmaceutica  Drug Research. Issue 6;2011.

4. Sanmukhani J, Shah V, Baxi N, Tripathi CB. Fixed drug eruption with ornidazole with cross- sensitivity to secnidazole but not to other nitro-imidazole compound: a case report. British Journal of Clinical Pharmacology, 2010;69: 703-4. 

5.Tripathi CB, Mistry SD, Bhavsar VH, Kelkar VV. Effect of repeated eletroconvulsive shocks and of chronis impramine treatment on salbutamol  induced inhibition of ingestive behaviour of rats. International Research Communication System Medical Science.1985;13: 846. 

6.Neuromuscular blocking effect of fluoxetine and its interaction with rocuronium in Auton Autacoid Pharmacol. 2013 Apr;33(1-2):17-24. 

7.Anti-Urolithiatic Effect of Ethanolic extract of Pedalium murex Linn. Fruits on Ethylene Glycol-Induced Renal Calculi in Urol J. 2013 Sep 26;10(3):946-52

8.Anti-Urolithiatic Effect of Cow Urine Ark on Ethylene Glycol-Induced Renal Calculi  Int Bra J.Urol. 2013; 39

9.Evaluation of Anti-Inflammatory, Analgesic, and Antipyretic Effect of Ethanolic Extract of Pedalium Murex Linn. Fruits. AJTCAM), Vol 10, No 4 (2013)

10.Effect of topical nitric oxide donor (0.2 % glyceryl trinitrate) on wound healing in diabetic wistar rats. International Journal of Diabetes in Developing Countries September 2013

11.Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial. Phytother Res. 2013 Jul 6. doi: 10.1002/ptr.5025

12.Anti-Urolithiatic Effect of Cow Urine Ark on EthyleneGlycol-Induced Renal Calculi Int Bra J.Urol. 2013; 39:
 

Research grants received 

1 To Study the Effect of N-acetyl Cysteine, Isoniazid and Ground nut oil for Reduction of Mortality due to Aluminium Phosphide Poisoning in Rabbits (50,000/- by Govt. of Gujarat)

2 A Randomized, Active Controlled, Open Label, Parallel Group Study to compare the efficacy of Extract of Curcuma Longa (Turmeric) with Fluoxetine and to study its effect as an add on therapy to fluoxetine in patients of mild to moderate depression. (25,000/- by Govt. of Gujarat)

3 Randomized Double Blind Parallel Group Comparative Study to Evaluate Efficacy and Safety of Triplet Combination (Ciclosonide, Tiotropium Bromide and Formoterol) and Dual Combination (Tiotropium Bromide and Formotero) in Mild to Moderate Cases of Chronic Obstructive Pulmonary Disease. (40,000/- by Govt. of Gujarat

4 Utilization Pattern of Antimicrobials Among Patients Undergone Midline Laparotomy in Four Tertiary Care Teaching Hospitals of Gujarat, India: Multi-Centric Retrospective Study (10,000/- by Govt. of Gujarat)

5 Interaction between rosuvastatin and rocuronium in rat sciatic-gastrocnemius nerve-muscle preparation. (25,000/- by ICMR Dissertation Grant)

6 Audit of antibiotic sensitivity pattern in critical care Unit (CCU), Pediatric intensive care Unit (PICU), Neonatal intensive care Unit (NICU) and intensive cardaiac care unit (ICCU) at a tertiary care Hospital: A retrospective study. (10,000/- by ICMR STS Program)

7 P drug- Knowledge, Attitude and Practice among undergraduate medical students. (10,000/- by ICMR STS Program)

8 Knowledge, Attitude and Actions towards body donation in the students of modern and alternative medicine. (10,000/- by ICMR STS Program)

9. Drug Utilization in elderly patients admitted in the medicine ward of a tertiary care Hospital: Pharmaco-Economic Aspect. (10,000/- by ICMR STS Program)

10. Prescribing Pattern in Patients of Asthma Visiting Outpatient Departments of a Tertiary Care Hospital: A Cross-Sectional, Observational Study. (10,000/- by ICMR STS Program)

11. Knowledge, Attitude and Practice Towards Prevention of Thalassemia in Normal and Thalassemia Minor Students ( 10,000/- by ICMR STS Program)

12. Knowledge and Attitude towards Emergency Contraception Among Undergraduate Medical Students. (10,000/- ICMR STS Program)

13. Comparison of Efficacy and Safety of Amitryptiline and Mirtazapine in Peripheral Diabetic Neuropathic Pain: A Randomized, Open Labelled, Parellel Group Study. ( 65,000/- by Govt. of Gujarat)

14. Efficacy and Safety of Tolperisone hydrochloride & Eperisone hydrochloride in Management of Acute Low Back Pain: A Comparative Randomized Double Blind Double Dummy Clinical trial. ( 25,000/- by Govt. of Gujarat)

15. Drug Utilization Pattern of Antimicrobial Agents in an Out Patients Department of Ottorhinolaryngology in a Tertiary Care Hospital: A Prospective Cross-sectional Study. (10,000/- by Govt. of Gujarat)

16. Impact of HIV Infection and Role of Corticosteroid Therapy in Drug Induced Stevens Johnson Syndrome: A Multicentric Retrospective Study. (7,000/- by Govt. of Gujarat)

17. Knowledge, Attitude and Practice about post-exposure prophylaxis for HIV in undergraduate clinic attending medical and nursing students. (5,000/- by Govt. of Gujarat)

18. Comparative Study of Efficacy and Safety of Amitryptiline versus Carbamazepine in Patients of Alcoholic Neuropathy: A Randomized, Parallel Group, Open Label Study. (30,000/- by Govt. of Gujarat)

Total grant = 3,62,000/- (Three lacs sixty two thousand only)

Collaborative Research Projects undertaken with various Institutes     

1."An Investigation into the molecular mechanism of action of Triticum Aestivum for its Activity in Thalassemia" in collaboration with Shantilal Shah Pharmacy College, Bhavnagar (PI- Dr. Prakash Shah).

2."Investigation of cardio protective effects of Tachomella Undulata and Triticum Aestivum" in collaboration with Shantilal Shah Pharmacy College, Bhavnagar (PI-Mr. Harshul Parekh).

3."Anti-inflammatory activity of Ethanolic Extract of Leaves, Bark and Flower from Cassia Siamen ( Lin.) and Cassia Javanica (Lin.)" in collaboration with Department of Chemistry, Bhavnagar University (PI-Mr. Pravin Parmar).

4."Montmorillonite Poly-L-Lactide Microcomposites of Procainamide for controlled drug delivery: In vitro and In vivo evaluation" in collaboration with CSMCRI, Bhavnagar (PI-Mr. Bhavesh Kevadiya).

5."Taste masking by functional cross-linked copolymers and sustain release of drug through interpenetrating polymer network with sodium alginate and K-carreganeen biopolymers" in collaboration with CSMCRI, Bhavnagar (PI- Mr. Michel Rajesh).

6."Effect of Sulphated Polysaccharide from Marine Algae in Ethylene Glycol-Induced Renal Stone in Wistar albino Rats" in collaboration with CSMCRI, Bhavnagar (PI- Dr. Amol Aiwale).

7."Effectiveness of neuraminidase inhibitors in reducing mortality in patients admitted to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of individual participant data" in collaboration with Nautighaum University (PI- Ms. Stella Muthuri).

8."Iron bioavailability Study from Double Fortified Salt (DFS) in Wistar albino rats" in collaboration with CSMCRI, Bhavnagar (PI- Dr. J. R. Chunawala).

9."Iodine and Iron bioavailability Study from Double Fortified Salt (DFS) in Wistar albino rats" in collaboration with CSMCRI, Bhavnagar (PI- Dr. J. R. Chunawala).

10."Effect of Myristica fragrans Nutmeg on Helicobacter Pylori induced Gastric Ulcer in Wistar Albino rats" in collaboration with Tropical School of Medicine, Kolkata (PI- Dr. Dharamvir Jadeja).

11"Bioavailability study of fenofibrate and its various formulations with nanocomposites after single dosing in New-Zealand white rabbits" in collaboration with New-Jersey Institute of Technology, USA (PI-Dr. C.B. Tripathi).

Case Reports Published in last five years  

1. Barvaliya MJ, Naik VN, Shah AC, Tripathi CB. Safety of Olmesartan in a patient with telmisartan induced myotoxicity: A case report. Br J Clin Pharmacol. 2014 Dec 11. 

2. Vachhani A, Barvaliya M, Naik V, Tripathi CB. Cardiovascular abnormalities with single dose of tapentadol. J Postgrad Med. 2014 Apr-Jun;60(2):189-91.

3. Patel K, Panchasara A, Purohit B, Tripathi CB. Nevirapine and/or co-trimoxazole induced Stevens Johnson syndrome in HIV infected patient--a case report. Curr Drug Saf. 2013 Feb;8(1):72-4.

4. Barvaliya MJ, Patel MK, Patel TK, Tripathi CB. Toxic epidermal necrolysis due to lamotrigine in a pediatric patient. J Pharmacol Pharmacother. 2012 Oct;3(4):336-8. 

5. Patel MK, Barvaliya MJ, Patel TK, Tripathi CB. Stavudine induced acute necrotizing pancreatitis with tetany in a pediatric patient. Indian J Pharmacol. 2012 Jul-Aug;44(4):523-5. 

6. Mandavia DR, Virpariya MM, Patel TK, Tripathi CB. Moxifloxacin-induced hypoglycemia in a non-diabetic patient. Curr Drug Saf. 2012 Apr;7(2):183-5.

7. Panchasara A, Mandavia D, Anovadiya AP, Tripathi CB. Central anti-cholinergic syndrome induced by single therapeutic dose of atropine. Curr Drug Saf. 2012 Feb;7(1):35-6.

8. Patel MK, Patel TK, Tripathi CB. Diphtheria, pertussis (whooping cough), and tetanus vaccine induced recurrent seizures and acute encephalopathy in a pediatric patient: Possibly due to pertussis fraction. J Pharmacol Pharmacother. 2012 Jan;3(1):71-3. 

9. Barvaliya M, Sanmukhani J, Patel TK, Tripathi CB. Phenytoin induced chorea in a pediatric patient: An interaction between phenytoin, phenobarbital and clobazam. Indian J Pharmacol. 2011 Nov;43(6):731-2.

10. Anovadiya AP, Barvaliya MJ, Patel TK, Tripathi CB. Cross sensitivity between ciprofloxacin and levofloxacin for an immediate hypersensitivity reaction. J Pharmacol Pharmacother. 2011 Jul;2(3):187-8.

11. Aiwale AS, Patel UA, Barvaliya MJ, Jha PR, Tripathi C. Isoniazid induced convulsions at therapeutic dose in an alcoholic and smoker patient. Curr Drug Saf. 2015;10(1):94-5.  

 

Systemic Review published in last five years

1. Patel TK, Patel PB, Barvaliya MJ, Tripathi C B. Drug-induced anaphylactic reactions in Indian population: A systematic review. Indian J Crit Care Med 2014;18:796-806.

2. Patel TK, Barvaliya MJ, Sharma D, Tripathi C. A systematic review of the drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Indian population. Indian J Dermatol Venereol Leprol. 2013 May-Jun;79(3):389-98.

Review articles published in last five years     

1. Sanmukhani J, Tripathi CB. Ethics in clinical research: the Indian perspective. Indian J Pharm Sci. 2011 Mar;73(2):125-30.

2. Anovadiya AP, Sanmukhani JJ, Tripathi CB. Epilepsy: Novel therapeutic targets. J Pharmacol Pharmacother. 2012 Apr;3(2):112-7.

3. TK Patel, MJ Barvaliya, CB Tripathi. Current Concept of Management of Stevens Johnson Syndrome and Toxic Epidermal Necrolysis. NMO journal 2014;8(2).

4. Tripathi CB, Vachani AV, Paliwal NP. Urinary Tract Infection: A Hidden Enemy. NMO journal 2015;9(1).

   Review articles published in last five years     

 

1. Sanmukhani J, Tripathi CB. Ethics in clinical research: the Indian perspective. Indian J Pharm Sci. 2011 Mar;73(2):125-30.

2. Anovadiya AP, Sanmukhani JJ, Tripathi CB. Epilepsy: Novel therapeutic targets. J Pharmacol Pharmacother. 2012 Apr;3(2):112-7.

3. TK Patel, MJ Barvaliya, CB Tripathi. Current Concept of Management of Stevens Johnson Syndrome and Toxic Epidermal Necrolysis. NMO journal 2014;8(2).

4. Tripathi CB, Vachani AV, Paliwal NP. Urinary Tract Infection: A Hidden Enemy. NMO journal 2015;9(1).

 

 Scientific Publications in last five years     

1. Patel JC, Patel PB, Acharya H, Nakum K, Tripathi CB. Efficacy and safety of lornoxicam vs ibuprofen in primary dysmenorrhea: a randomized, double-blind, double dummy, active-controlled, cross over study. Eur J Obstet Gynecol Reprod Biol. 2015 Mar 9;188:118-123.
2. Panchasara AK, Patel JC, Vadgama VK, Barvaliya MJ, Tripathi CB. Interaction between rosuvastatin and rocuronium in rat sciatic-gastrocnemius nerve-muscle preparation. J Anesth. 2014 Oct;28(5):727-32.
3. Kevadiya BB, Patel TK, Patel PB, Rajkumar S, Tripathi CB, Bajaj HC. Montmorillonite Poly-L-lactide microcomposites of procainamide for controlled drug delivery: In vitro and in vivo evaluation. Indian J Pharm Sci 2013;75:722-6.
4. Jhaveri BN, Patel TK, Barvaliya MJ, Tripathi C B. Drug utilization pattern and pharmacoeconomic analysis in geriatric medical in-patients of a tertiary care hospital of India. J Pharmacol Pharmacother 2014;5:15-20.
5. Patel MK, Barvaliya MJ, Patel TK, Tripathi C B. Drug utilization pattern in critical care unit in a tertiary care teaching hospital in India. Int J Crit Illn Inj Sci 2013;3:250-5.
6. Barvaliya M J, Patel T K, Patel J C, Tripathi C B. Effect of zidovudine and its interaction with rocuronium on neuromuscular transmission. Indian J Pharm Sci 2013;75:191-6.

7. Kevadiya BD, Patel TA, Jhala DD, Thumbar RP, Brahmbhatt H, Pandya MP, Rajkumar S, Jena PK, Joshi GV, Gadhia PK, Tripathi CB, Bajaj HC. Layered inorganic nanocomposites: a promising carrier for 5-fluorouracil (5-FU). Eur J Pharm Biopharm. 2012 May;81(1):91-101.


8. Goswami NN, Trivedi HR, Goswami AP, Patel TK, Tripathi CB. Antibiotic sensitivity profile of bacterial pathogens in postoperative wound infections at a tertiary care hospital in Gujarat, India. J Pharmacol Pharmacother. 2011 Jul;2(3):158-64.

9. Anovadiya AP, Barvaliya MJ, Shah RA, Ghori VM, Sanmukhani JJ, Patel TK, Tripathi CB. Adverse drug reaction profile of oseltamivir in Indian population: A prospective observational study. Indian J Pharmacol. 2011 May;43(3):258-61. 

10. Vora MB, Trivedi HR, Shah BK, Tripathi CB. Adverse drug reactions in inpatients of internal medicine wards at a tertiary care hospital: A prospective cohort study. J Pharmacol Pharmacother. 2011 Jan;2(1):21-5. 


11. Patel PB, Patel TK, Shah P, Baxi SN, Sharma HO, Tripathi CB. Protective Effect of Ethanol Extract of Gymnosporia montana (Roth) Bemth. in Paracetamol-induced Hepatotoxicity in Rats. Indian J Pharm Sci. 2010 May;72(3):392-6. 

12. Patel YA, Patel P, Bavadia H, Dave J, Tripathi CB. A randomized, open labeled, comparative study to assess the efficacy and safety of controller medications as add on to inhaled corticosteroid and long-acting β2 agonist in the treatment of moderate-to-severe persistent asthma. J Postgrad Med. 2010 Oct-Dec;56(4):270-4. 

13. Patel TK, Patel PB, Tripathi CB. Effect of pantoprazole and its interactions with vecuronium on the neuromuscular junction. Indian J Pharmacol. 2010 Feb;42(1):36-9. 

14. Anovadiya AP, Sanmukhani JJ, Vadgama VK Tripathi CB. Evaluation of antiepileptic and memory retention activity of curcumin per se and in combination with antiepileptic drugs. Asian J Pharm Clin Res 2013;6(2):145-8.
15. Anovadiya AP, Sanmukhani JJ, Vadgama VK Tripathi CB. Evaluation of antiepileptic and memory retention activity of curcumin per se and in combination with antiepileptic drugs. Asian J Pharm Clin Res 2013;6(2):145-8.

16. Chawda HM, Mandavia DR, Parmar PH, Baxi SN, Tripathi CR. Hypolipidemic activity of a hydroalcoholic extract of Cyperus scariosus Linn. root in guinea pigs fed with a high cholesterol diet. Chin J Nat Med. 2014 Nov;12(11):819-26. 

17. Patel PB, Patel TK, Baxi SN, Acharya HR, Tripathi C. Antitubercular effect of 8-[(4-Chloro phenyl) sulfonyl]-7-Hydroxy-4-Methyl-2H-chromen-2-One in guinea pigs. J Pharmacol Pharmacother. 2011 Oct;2(4):253-60. 

18. Vora MB, Trivedi HR, Shah BK, Tripathi CB. Adverse drug reactions in inpatients of internal medicine wards at a tertiary care hospital: A prospective cohort study. J Pharmacol Pharmacother. 2011 Jan;2(1):21-5.

 

Other

M.D. Pharmacology    

Medical Council of India has given the permission to start the M.D. Pharmacology with three seats per year from April 2007.

Research Publications/Presentations     

1. Interactions between H 2 Receptor Blockers and A Neuromuscular Blocker in Vivo
Ujjwala Vaidya, Tripathi C.B. And Bhatt J. D.
XII annual Conference of Indian Pharmacological Society-Guj. Chapter 2- 3-97.

2. Interaction between H 2 Receptor Blocker and A Neuromuscular Blocker in Vitro
Choksi S. C., Tripathi C. B., Bhatt J. D. And Hemavathy K. G. 
XXX Annual Conference of Indian Pharmacological Society, 14 to 16-11-97

3. Comparative Study Of Beta Adrenoceptor Bloking Efficacy Of The Two
Formulations of Esmolol In Vivo And In Vitro
Tripathi C. B., Bhattacharya P., Bhatt J. D. And Hemavathy K. G. 
Indian Journal Of Physiology And Pharmacology, 1999, 43 (2), 255,258.

4. Interaction Between Pipacuronium And Famotidine & Roxatidine In Vivo
Trivedi Hiren, Tripathi C. B. And Bhatt J. D. 
XV Annual Conference of Indian Pharmacological Society-Guj. Chapter 1999.

5. Effect Of Nitrofurantoin on Contractile Responses Of Skeletal And Smooth Muscles
D .S. Shah, Dinita Shah, D. C. Sharma and B. K. Shah
XV Annual Conference of Indian Pharmacological Society-Guj. Chapter 1999.